Diabetes, Obesity, and Weight Loss: An Update

New findings and guidelines translate into better awareness, understanding, and clinical decision making.

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"...by 2025, global obesity prevalence will reach 18% in men and surpass 21% in women..." The Lancet, April 2016

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New guidelines from 2nd Diabetes Surgery Summit help prioritize when surgical treatment for DM is indicated.

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Maintenance of ~10% weight loss may reverse prediabetes and reduce significantly the risk of progression to DM.

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Research on long-term metabolic and physiologic effects of bariatric surgery may inform obesity and DM treatment strategies.

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Family history of DM, CVD associated with unfavorable metabolic markers in offspring.

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Obese patients with type 2 diabetes mellitus (DM) can ameliorate the consequences of obesity by losing weight. Click through the slides above for highlights of: ► New guidelines that inculde bariatric surgery as an option for some persons with obesity and type 2 DM. ► An international study that suggests weight loss could be the key to reversing prediabetes. ► A new review that summarizes long-term metabolic effects of gastric bypass surgery. ► A birth cohort study that shows an independent association between family history of DM or myocardial infarction and unfavorable cardiometabolic markers in young children.  

References:

1. Rubino F, Nathan DM, Eckel RH, et al. Metabolic surgery in the treatment algorithm for type 2 diabetes: a joint statement by international diabetes organizations.Diabetes Care. 2016; 39:861-877.

2. PREVIEW (PREVention of diabetes through lifestyle Intervention and population studies in Europe and around the World). Presented at European Obesity Summit. Gothenburg, Sweden. June 1, 2016.

3. Mosinski JD, Kirwan JP. Longer-term physiological and metabolic effects of gastric bypass surgery.Curr Diab Rep. 2016;16:50.

4. Berentzen NE, Wijga AH, van Rossem L, et al. Family history of myocardial infarction, stroke and diabetes and cardiometabolic markers in children.Diabetologia. 2016 May 30. [Epub ahead of print]


*Opening slide reference:

NCD Risk Factor Collaboration. Trends in adult body-mass index in 200 countries from 1975 to 2014: a pooled analysis of 1698 population-based measurement studies with 19·2 million participants. Lancet. 2016;387:1377-1396.