Neurology

 
9 Clinical Signs and Symptoms of Migraine Prodrome: At-a-Glance for Primary Care
October 02, 2025

The premonitory constellation of neurologic, autonomic, and behavioral symptoms are increasingly understood as the earliest manifestations of migraine pathophysiology.

Linus Health Will Highlight Digital Innovations in Early Detection of Cognitive Decline at FMX 2025
October 02, 2025

Linus Health will demonstrate advances in remote assessment platforms and digital biomarkers of cognitive health that can bring precision medicine to primary care.

FDA Grants Fast Track Designation to Anti-MTBR Tau Antibody BMS-986446 for Alzheimer Disease
October 01, 2025

The FDA has granted fast track designation to BMS-986446, an anti–microtubule binding region tau antibody in phase 2 trials for early Alzheimer disease.

Donanemab (Kisunla) Authorized in Europe for Early Symptomatic Alzheimer Disease
September 29, 2025

The European Commission granted marketing authorization for the Lilly mAb based on data from the phase 3 TRAILBLAZER-ALZ 2 and 6 clinical trials.

Alcohol Use at Any Level Linked to Higher Dementia Risk, Large Study Finds
September 24, 2025

A study of more than 559 000 adults and 2.4 million genetic samples found that alcohol consumption of any amount increases dementia risk, challenging prior evidence of protective effects from light drinking.

Leucovorin Close-Up: A Primary Care Primer
September 24, 2025

The FDA has initiated approval of leucovorin calcium tablets for children with cerebral folate deficiency, which can manifest with autistic features. What is it?

Emerging Tau-Targeting Antibody for Alzheimer Disease Receives FDA Fast Track Designation
September 23, 2025

FDA grants Fast Track designation to etalanetug, a promising tau-targeting antibody for Alzheimer disease that could expand treatment options for the neurodegenerative disease.

Vaginal Estradiol Shows No Added Risk of Repeat Stroke in Women: Daily Dose
September 19, 2025

Your daily dose of the clinical news you may have missed.

Alzheimer Disease: New Brain Targets and the New Drug Pipeline
September 17, 2025

Among 180+ active AD trials, 15 biological targets span traditional Aβ and tau proteins as well as new pathways in brain metabolism, neuroinflammation, and synaptic health.