Neurology

 
Treatment for Agitation in Alzheimer Dementia: Pipeline Preview with George Grossberg, MD
November 20, 2024

"It's a very rich pipeline because [agitation] is a very common and very debilitating symptom in Alzheimer's disease," Grossberg observed.

Exercise of Any Level Linked to Reduced All-Cause Mortality in Individuals with Dementia
November 19, 2024

Physical activity of any level before and after a diagnosis of dementia was associated with at least a 20% lower risk for all-cause mortality across dementia subtypes.

Agitation in Alzheimer Disease and Antipsychotics Used Off-Label are Not Meant for Each Other
November 18, 2024

Antipsychotic medications are still used to treat potentially harmful acute agitation, George Grossberg, MD, explains, even though the adverse effects are well known.

European Medicines Agency Reverses Opinion on Lecanemab for Alzheimer Disease But Limits Eligible Population
November 15, 2024

The EMA recommendation excludes from treatment adults who are homozygous for the ApoE ε4 gene, a decision that the US Alzheimer's Association does not support, said the president/CEO.

Nonpharmacologic Options for Agitation in Alzheimer Disease Should Always Come First: Expert Insights
November 15, 2024

Nondrug approaches to calming an adult with Alzheimer disease who is agitated should be prioritized over pharmacotherapy, geriatric psychiatrist George Grossberg, MD, counsels.

Environment is a Primary Nonpharmacologic Intervention to Reduce Agitation in Alzheimer Disease, Geriatric Psychiatrist Explains
November 14, 2024

When a patient with Alzheimer dementia becomes agitated, check the physical environment for a trigger before pulling the trigger on a medication, dementia expert George Grossberg, MD, recommends.

Alzheimer Disease Insights: It's Not All About Cognition, Counsels George Grossberg, MD
November 13, 2024

The geriatric psychiatrist refers in this interview to agitation in Alzheimer disease, a significant neuropsychiatric symptom that should not be dismissed.

Adjusted Donanemab Dosing Lowers ARIA-E Risk in Early Alzheimer Disease: Daily Dose
November 13, 2024

Your daily dose of the clinical news you may have missed.

Obstructive Sleep Apnea Linked to Increased Risk for Dementia, Particularly in Women
November 12, 2024

Michigan Medicine researchers found that at all age levels, women with known/suspected OSA were more likely than men to be diagnosed with dementia.

Among Stroke Survivors, GLP-1RAs, SGLT2is May Reduce Risk of Future MI, Recurrent Stroke
November 11, 2024

AHA 2024. Study authors reported a 74% lower risk of death and an 84% lower risk of MI among participants taking either a GLP-1RA or an SGLT2i.