4 New Developments in Diabetes

Here: a brief overview of 4 recent diabetes developments, including a call for a new way to classify the disease and a new online test for prediabetes.

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New developments in diabetes you may have missed.

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The dysfunctional β-cell is the common denominator in all diabetes, regardless of the subtype or category. The author proposes that a β-cell centered schema would be more clinically useful and lead to more optimal patient care. Underutilized treatments could become rational choices to target individual mediating pathways of hyperglycemia.

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Living with type 2 diabetes tends to increase the risk of depression. Is duration of diabetes a direct or indirect cause of depression in later life? Finding: Living with diabetes for >30 years triples the risk of depression. Frailty could explain some of the association. Strategies that decrease diabetes-related complications also may reduce the risk of depression among older men.

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Antipsychotics taken for nonpsychotic and off-label indications may raise the risk of cardiometabolic adverse effects, especially type 2 diabetes in young people. Findings: study found that the cumulative risk of T2D was 2.5 times higher in youths who took antipsychotics than in healthy controls. Implications: Antipsychotics should be used judiciously and for the shortest time frame for young patients.

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Close to 90% of the ~86 million Americans who have prediabetes are unaware that they have the condition. A new joint awareness campaign was launched by the ADA, AMA, CDC, and Ad Council:

Type 2 Diabetes Prevention.

Includes a real-time 60-second TV commercial prediabetes test and an online 7- question risk test (DoIHavePrediabetes.org.).

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This very brief overview of 4 recent developments in type 2 diabetes includes: a call for a new way to classify the disease using dysfunctional β-cells, a link between the duration of depression and diabetes, increased risk of diabetes in young patients with antipsychotics, and a new online test for prediabetes.  

References:

1. Schwartz SS. The time is right for a new classification system for diabetes: rationale and implications of the B-cell-centric classification schema.Diabetes Care. 2016;39:179-186.

2. Almeida OP, McCaul K, Hankey GJ, et al. Duration of diabetes and its association with depression in later life: The Health In Men Study (HIMS). Maturitas. Published online January 11, 2016.

3. Galling B, Roldán A, Nielsen RE, et al.  Type 2 diabetes mellitus in youth exposed to antipsychotics.JAMA Psychiatry. Published online January 20, 2016.

4. Press release. First-of-its-kind PSA campaign targets the 86 million American adults with prediabetes. American Diabetes Association. January 21, 2016.

Web site: So, do I have prediabetes? Ad Council. DoIHavePrediabetes.org. Accessed February 1, 2016.