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Weekly Dose Podcast: Depression Risk After Chronic Illness, Vaginal Estradiol Safety, GLP-1 Updates, Cancer Risk Reduction, and Cardiovascular Outcomes
September 24, 2025

Today's episode covers depression risk after chronic illness, vaginal estradiol safety, GLP-1 updates, cancer risk, and cardiovascular outcomes.

Alcohol Use at Any Level Linked to Higher Dementia Risk, Large Study Finds
September 24, 2025

A study of more than 559 000 adults and 2.4 million genetic samples found that alcohol consumption of any amount increases dementia risk, challenging prior evidence of protective effects from light drinking.

Leucovorin Close-Up: A Primary Care Primer
September 24, 2025

The FDA has initiated approval of leucovorin calcium tablets for children with cerebral folate deficiency, which can manifest with autistic features. What is it?

GRAIL to Showcase New Data for Galleri Multicancer Early Detection Test at Key Fall Meetings
September 24, 2025

New data will be shared from the PATHFINDER 2 study in asymptomatic patients and the SYMPLIFY study in patients experiencing symptoms.

Age and Aerobic Fitness Independently Linked to Atrial Arrhythmia Risk: Daily Dose
September 24, 2025

Your daily dose of the clinical news you may have missed.

Cervical Cancer Screening: What Primary Care Physicians Need to Know
September 23, 2025

PODCAST: Family physician Ada Stewart, MD, shares practical strategies for cervical cancer screening and patient communication.

Emerging Tau-Targeting Antibody for Alzheimer Disease Receives FDA Fast Track Designation
September 23, 2025

FDA grants Fast Track designation to etalanetug, a promising tau-targeting antibody for Alzheimer disease that could expand treatment options for the neurodegenerative disease.

Investigational IL-2 Pathway Agonist Rezpegaldesleukin Shows Promise in Phase 2b REZOLVE-AD Trial
September 23, 2025

The findings highlight rezpegaldesleukin's novel broad-based Treg mechanism, suggesting it may be a potent option with potential for disease modification in atopic dermatitis.

HHS Ties Acetaminophen Use During Pregnancy to Autism, Despite Widely Conflicting Evidence
September 23, 2025

The administration has initiated a nationwide public service campaign about the potential risks as professional societies quickly disputed the claims.

Semaglutide Shows Greater CVD Risk Reduction Than Tirzepatide in Adults With Obesity: Daily Dose
September 23, 2025

Your daily dose of the clinical news you may have missed.