All News

Nerandomilast Meets Primary Endpoint in Phase III FIBRONEER-ILD Trial in Progressive Pulmonary Fibrosis
February 11, 2025

Topline data announced by Boehringer Ingelheim for the PDE4B inhibitor showed a statistically significant absolute change from baseline in FVC at week 52 vs placebo.

Heart Disease Remains Leading Cause of Death in US: Daily Dose
February 11, 2025

Your daily dose of the clinical news you may have missed.

Suzetrigine (Journvax) Fits Neatly in a Multimodal Strategy to Manage Acute Pain, According to Edward Mariano, MD, MAS
February 11, 2025

Multimodal pain management expert and researcher Mariano describes the NaV1.8 inhibitor as "working in concert" with nonopioid therapies, including nerve blocks.

Headaches and Suicide
February 10, 2025

The risk of a suicide attempt was 2 times greater among those with headache, across types including tension type headache, migraine, trigeminal autonomic cephalalgia, and posttraumatic headache.

FDA Grants Fast Track Designation to Rezpegaldesleukin for Atopic Dermatitis
February 10, 2025

Rezpegaldesleukin targets the IL-2 receptor complex to stimulate regulatory T cells, aiming to restore immune balance in people with atopic dermatitis.

FDA Accepts BLA for Lerodalcibep, Novel PCSK9 Inhibitor to Lower LDL-C
February 10, 2025

The FDA set a PDUFA action date of December 12, 2025 for lerodalcibep, according to LIB Therapeutics.

Elevated Suicide Risk Identified in People with Headache Disorders
February 10, 2025

Post-traumatic headaches and trigeminal autonomic cephalalgia significantly increased the risk for attempted and completed suicide, according to new study.

Use of Perioperative Multimodal Pain Management in the US Remains Low, Expert Says
February 10, 2025

An anesthesiologist and renowned investigator in use of nonopioids as part of multimodal pain management, Edward Mariano, MD, MAS, describes slow uptake in the field.

Vistagen Wins US Patent for Investigational NMDA Receptor Antagonist to Treat Neuropathic Pain
February 10, 2025

AV-101 is an orally bioavailable small molecule NMDA receptor antagonist with antinociceptive effects similar to gabapentin but with more a more favorable safety profile.

FDA Approves Nonopioid Journavx for Acute Pain: Daily Dose
February 10, 2025

Your daily dose of the clinical news you may have missed.