Hepatic Disease

 
Underrepresentation of Individuals with CKD in CV Medication Trials Found Persistent Over 2 Decades
March 08, 2024

Authors: Exclusion of people with CKD from CV medication trials has left significant gaps in understanding the effectiveness of these drugs in a highly vulnerable population.

Resmetirom for NASH: MASESTRO-NASH Phase 3 Data in NEJM Precede PDUFA Date of 3-14-2024
March 04, 2024

Resmetirom vs placebo led to significantly greater proportion of adults reaching NASH resolution without increased fibrosis and with fibrosis improvement by ≥1 stage.

Survodutide, Dual Glucagon/GLP-1 Mimetic, Improves MASH in 83% of Phase 2 Trial Participants
February 27, 2024

The statistically significant improvements in MASH with survodutide were seen without worsening fibrosis and included a relative reduction of steatosis of 30%.

SGLT2 Inhibitors Outperformed Other Oral Antidiabetic Drugs for Persons with T2D, NAFLD: Daily Dose
February 20, 2024

Your daily dose of the clinical news you may have missed.

SGLT2 Inhibitors Outperformed Other Oral Antidiabetic Drugs for Patients with T2D and NAFLD, According to New Research
February 12, 2024

Findings suggest that SGLT2 inhibitors may be the preferred choice for patients with both T2D and NAFLD, reported researchers.

Noninvasive Tests May be Poor Predictor of Liver Fibrosis, Especially Among Black Adults
February 06, 2024

Using FIB-4 index first to screen for cirrhosis may lead to clinicians missing 48% of cases, according to a recent study.

Alcohol-Related Liver Disease May be More Deadly Among Women than Men, Study Suggests
January 31, 2024

Risk of mortality from ALD and MetALD was significantly higher among women even though both phenotypes were more prevalent among men, a new study reveals.

Daily Dose: Lack of Osteoporosis Screening, Treatment in Patients with Cirrhosis
January 19, 2024

Your daily dose of the clinical news you may have missed.

Daily Dose: NAFLD Associated with Adverse Outcomes Regardless of BMI
January 16, 2024

Your daily dose of the clinical news you may have missed.

Fibrosis Screening Results May Motivate Behavior Change in Adults at Risk of Liver Disease: Danish Study
January 16, 2024

Screening for fibrosis in persons at risk of ALD and MASLD led to sustained improvements in lifestyle, eg, reduced alcohol consumption, weight loss, and increased exercise.