Lipid disorders

 
Oral PCSK9 Inhibitor Enlicitide Meets All End Points in Phase 3 Hypercholesterolemia Trial
September 02, 2025

At week 24, patients receiving once-daily enlicitide demonstrated statistically significant and clinically meaningful reductions in low-density lipoprotein cholesterol compared with placebo.

FDA Expands Evolocumab Indication to Adults at Risk for Major Cardiovascular Events Due to Uncontrolled LDL-C
August 26, 2025

The FDA removed the prior requirement for a person who is already diagnosed with a cardiovascular disease.

RDX-002 Hits Primary and Secondary End Points for Post–GLP-1 Weight Management
August 14, 2025

RDX-002, an investigational, first-in-class therapeutic, significantly reduced weight regain after cessation of antiobesity treatment with semaglutide and tirzepatide.

FDA Label Update Positions Inclisiran as First-Line Monotherapy for Hypercholesterolemia
August 01, 2025

Inclisiran can now be used without a background statin, as an adjunct to changes in diet and physical activity for reduction of LDL-C in hypercholesterolemia.

FDA Accepts BLA for Lerodalcibep, Novel PCSK9 Inhibitor to Lower LDL-C
February 10, 2025

The FDA set a PDUFA action date of December 12, 2025 for lerodalcibep, according to LIB Therapeutics.

Strong Link Between Increasing Lp(a) Level and Recurrent ASCVD Events Makes Screening Essential, Investigator Warns
September 25, 2024

A continuous increase in ASCVD risk was seen with higher levels of lipoprotein(a) in the largest study to date of the relationship.

Dyslipidemia in American Indian Youth: Daily Dose
March 15, 2024

Your daily dose of the clinical news you may have missed.

New Data Show High Prevalence of Dyslipidemia in American Indian Youth
March 08, 2024

Few participants with dyslipidemia received lipid-lowering medications despite high prevalence, reported authors of the Strong Family Heart Study.

Consuming More Food, Beverages with Added Sugar Linked to Greater Risk for Metabolic Syndrome
January 15, 2024

Compared to the lowest intake of AS-rich food and beverages, the highest intake was associated with a 59% higher risk of developing MetS, according to new findings.

Daily Dose: Cardiovascular Risk Factors Rising Among Middle-Aged Americans
December 04, 2023

Your daily dose of the clinical news you may have missed.