Obesity and Venous Disease: Risk Factors and Key Diagnostic Challenges
August 21, 2025

Shagun Bindlish, MD, board member of the American Diabetes Association, discusses challenges to diagnosing and treating venous disease in patients with obesity.

With Medical Societies "Uninvited" From ACIP Vaccine Working Groups, Is There Any Hope for Harmonized Schedules?
August 21, 2025

William Schaffner, MD, a long-time liaison from the NFID to the ACIP working groups, is concerned about fragmentation of US vaccine recommendations.

Atumelnant for Congenital Adrenal Hyperplasia Agent Granted FDA Orphan Drug Designation
August 21, 2025

The FDA's ODD award is based on the positive findings from the phase 2 TouCAHn trial, which also support Crinetics' robust phase 3 pivotal clinical trial program for the novel agent.

Vaginal Estradiol Not Linked to Recurrent Ischemic Stroke in Women With Prior Stroke
August 21, 2025

Vaginal estradiol is often prescribed as first-line therapy for genitourinary syndrome of menopause, making the findings supportive of current clinical practice.

Use of Digital Twin Technology Enabled Significant HbA1c Reduction and Medication Tapering in Primary Care T2D Management
August 21, 2025

A Cleveland Clinic trial revealed that AI-driven precision treatment significantly reduced HbA1c and body weight, often eliminating need for medications other than metformin.

Mailed FIT Kits Boost CRC Screening at Ages 45–49: Daily Dose
August 21, 2025

Your daily dose of the clinical news you may have missed.

Risk of Major Depressive Disorder Spikes Following a Medical Diagnosis, Endures for Decades: New Data
August 20, 2025

The risk for MDD is greatest in the first month after diagnosis and the absolute risk remains elevated even 20 years later, making early detection and treatment imperative.

First Oral Penem Antibiotic Now Available in the US for Uncomplicated UTIs
August 20, 2025

The first oral penem antibiotic, Orlynvah™, has launched in the US, offering a vital treatment option for women with resistant uncomplicated UTIs.

The Weekly Dose: Nutrition Gaps, Tau Pathology in Mood Disorders, RSV Protection, and More
August 20, 2025

This week’s roundup covers nutrition counseling barriers, tau pathology in mood disorders, RSV protection, AD patient needs, and a new Shingrix syringe.

How to Talk to Patients About Respiratory Virus Vaccines This Year? The Same Way We Always Do
August 20, 2025

William Schaffner, MD, advises first and foremost to stay away from politics, to acknowledge and normalize patient fear and concern, and to answer quickly and with confidence.