Exclusive Survey Results: Screening For Cognitive Decline in Primary Care

New survey finds that most PCPs screen for mild cognitive impairment, but time is an issue, guidelines are few, and low levels of confidence persist.

Metformin May Be Effective Treatment for Atrial Fibrillation in Adults wtih Obesity and Without Diabetes
November 12, 2025

Research reveals metformin's potential to enhance sinus rhythm stability post-ablation for AF in adults with obesity, independent of weight loss.

Digital Screening Tool Duo Shows Promise for ADRD Detection in Primary Care
November 12, 2025

Indiana University study found that integrating patient-reported outcome questionnaires with machine learning boosts dementia diagnoses by 31% in primary care settings.

Large-Scale Study Challenges Previous Research on Menopause and Brain Structure
November 11, 2025

TMS 2025: Katrina Wugalter, MA, discusses research showing that age—not menopause stage—drives brain volume decline, and how lifestyle factors can help preserve brain health in midlife women.

Mayo Clinic Researcher on Why Menopause Stage Matters in Metabolic Research
November 11, 2025

TMS 2025: Regina Castaneda, MD, explains why reproductive stage is a critical variable in obesity and metabolic research.

Tapinarof Cream 1%, Shows Early and Durable Response in Children With Atopic Dermatitis
November 11, 2025

ACAAI 2025. Phase 3 data show tapinarof cream provides early, sustained improvement and good tolerability in children aged ≥2 years with atopic dermatitis.

Vitamin D Dosing Tailored to Optimal Levels Reduced Risk of Recurrent MI by More Than Half
November 11, 2025

The TARGET-D trial found targeted vitamin D dosing post-MI didn’t lower MACE but reduced recurrent MI risk, supporting individualized serum-level management.

Cushing Syndrome: Clinical Features, Screening Tests, and When to Refer
November 11, 2025

Recognize Cushing syndrome in primary care: key clinical clusters, first-line screening tests (DST, salivary cortisol, UFC), and when to refer to endocrinology.

Sublingual Epinephrine Film Well Tolerated in Children, Matches Efficacy Seen in Adults
November 10, 2025

Sublingual epinephrine film matches adult PK/PD in kids aged 7-17 with a history of allergic reactions and high risk for serious allergic reactions, incluing anaphylaxis.

FDA to Remove “Black Box” Warnings from Hormone Replacement Therapy Products
November 10, 2025

Regulatory update aims to align labeling with current evidence on menopausal hormone therapy safety and benefits

Investigational Oral PCSK-9 Inhibitor Reduces LDL-C by 60% in Late Stage HeFH Trial
November 10, 2025

Merck's oral PCSK9 inhibitor enlicitide demonstrated antibody-like LDL-C lowering in adutls with HeFH with safety profile similar to placebo in phase 3 trial.