FDA Accepts Protocol for Annovis Bio’s Buntanetap Phase 3 Alzheimer Disease Trial
January 09, 2025

Buntanetap is an oral molecule designed to inhibit the production of multiple neurotoxic proteins and is under investigation for treatment of Alzheimer Disease, Parkinson’s Disease, and other neurodegenerative diseases.

Viking Therapeutics Launches Phase 2 Trial for Oral VK2735 in Patients with Obesity
January 09, 2025

The trial builds on results from a previous phase 1 study that showed dose-dependent weight loss and favorable tolerability for VK2735 in people with obesity.

Elinzanetant Meets All Endpoints in Phase 3 Study of VMS Caused by Adjuvant Endocrine Therapy for Breast Cancer
January 09, 2025

Elinzanetant produced a statistically significant reduction in frequency of treatment-related vasomotor symptoms as early as week 1 and in severity at weeks 4 and 12.

New Guidelines on Diagnosing Alzheimer’s Disease and Related Cognitive Impairments: A Comprehensive Framework for Primary Care
January 09, 2025

The first US interdisciplinary evaluation guideline will help primary care clinicians address the rising prevalence of AD and ADRD seen in their front-line clinical setting.

Mobile App Shows Promise for Hypertension Management: Daily Dose
January 09, 2025

Your daily dose of the clinical news you may have missed.

FDA Updates RSV Vaccine Labels to Include Guillain-Barré Syndrome Warning
January 08, 2025

The FDA approved the addition of Guillain-Barré syndrome warnings for Abrysvo and Arexvy, citing postmarketing data suggesting an increased risk.

FDA Proposes Sustained 5% Weight Loss to Establish Efficacy of New Antiobesity Medications
January 08, 2025

In an unusual step, the agency's draft guidance recommends the efficacy benchmark for drug approval while emphasizing clinical trial structure and cohort development.

FDA Grants Fast Track Designation to Posdinemab for Early Alzheimer's Disease
January 08, 2025

Johnson & Johnson's posdinemab aims to slow tau pathology in early and preclinical Alzheimer’s disease populations.

FDA OKs Tapinarof Cream, 1% for Atopic Dermatitis In Patients Aged 2 Years and Older: Daily Dose
January 08, 2025

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Migraine Therapeutics Research that Made News with Neurologists in 2024: Interview with Peter McAllister, MD
January 08, 2025

Significant strides were made in 2024 in evaluating a wide range of treatments for migraine, including phase 2 findings with PACAP inhibition, PI McAllister said.