Exclusive Survey Results: Screening For Cognitive Decline in Primary Care

New survey finds that most PCPs screen for mild cognitive impairment, but time is an issue, guidelines are few, and low levels of confidence persist.

Phase 3 Data Support Oral Orforglipron for Weight Maintenance After GLP-1–Based Weight Loss
December 19, 2025

Topline Phase 3 ATTAIN-MAINTAIN data show oral orforglipron met primary and key secondary endpoints for weight maintenance after prior GLP-1–based injectable therapy in adults with obesity.

Colonoscopy May be the Gold Standard, But Now It's a CRC Screening Bottleneck, Says Mark Fendrick, MD
December 19, 2025

Completion of the screening pathway—not test selection alone—may define quality going forward.

When Daily Oral PrEP Is Not the Best Fit: Lessons From Clinical Practice
December 19, 2025

Real-world patient cases illustrating how pill burden, privacy, and individual preferences influence PrEP selection and adherence.

Moderate-to-Severe OSA Tied to Doubled Risk of Brain Microbleeds: Daily Dose
December 19, 2025

Your daily dose of the clinical news you may have missed.

Tezepelumab Achieves Dual Benefit in Adults with Severe Asthma: Daily Dose
December 18, 2025

Your daily dose of the clinical news you may have missed.

FDA Approves Lerodalcibep, Third-Generation PCSK9 Inhibitor, to Treat Hypercholesterolemia, Including HeFH
December 18, 2025

Phase 3 LIBerate data showed sustained LDL-C reductions of 60% or more in high-risk patients and 50% or more in HeFH, with once-monthly self-administration.

How Long-Acting Injectable PrEP Reshapes the Patient–Provider Relationship
December 18, 2025

Primary care physician Kevin Hatfield, MD, discusses how the switch can increase patient touchpoints, free cognitive burden, and strengthen long-term engagement between patients and PCPs.

In CRC Screening, Progress Looks More Like Improved Follow-Through vs Next Breakthrough: Discussion with Mark Fendrick, MD
December 18, 2025

Moving patients from considering screening to completing it remains the central challenge in colorectal cancer prevention, Fendrick explained to Patient Care.

Zasocitinib Demonstrates Superiority vs Placebo and Apremilast in Phase 3 Plaque Psoriasis Trials
December 18, 2025

Zasocitinib showed significant efficacy in treating moderate-to-severe plaque psoriasis, outperforming placebo and apremilast in pivotal phase 3 trials.